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Industrial systems, such as aero engine, power network, chemical automation process, wind turbine systems, and so forth, are safety-critical systems. Therefore, there is an ever-increasing demand to provide a high-level system reliability and safety for practical engineering systems by implementing real-time monitoring, fault diagnosis, prognosis and tolerant control and management. This special session aims to provide a platform for the researchers and participants from both academic community and industrial sectors to report recent research and application progress in the field of condition monitoring, fault diagnosis, fault prognosis, tolerant control and their applications.